Subscribe to RSS
DOI: 10.1055/s-2002-19589
Therapie des akuten Nierenversagens[1]
Treatment of acute renal failurePublication History
Manuskript-Eingang: 29. Oktober 2001
Annahme nach Revision: 21. November 2001
Publication Date:
17 January 2002 (online)

Nach wie vor ist die einzige kausale Behandlung des akuten Nierenversagens (ANV) die Therapie der Grundkrankheit, sei sie extrarenal - oder renal - bedingt. Präventive Maßnahmen und Therapiekonzepte in der Initialphase des ANV sind daher von herausragender Bedeutung. Eine spezifische Therapie ist bei prärenaler Azotämie oder obstruktiver Nephropathie möglich, nicht jedoch bei manifestem ANV aufgrund ischämisch- toxischer Tubulusnekrose. Ziel geeigneter supportiver Maßnahmen und des adäquaten Einsatzes der Nierenersatztherapie ist es, lebensbedrohliche Komplikationen des vollständigen Verlustes der exkretorischen Nierenfunktion zu vermeiden.
1 Der Beitrag »Diagnostik des akuten Nierenversagens« ist im vorhergehenden Heft (Nr. 1/2) erschienen.
Literatur
- 1
Abramson S, Singh A K.
Continous renal
replacement therapy compared with intermittend hemodialysis in intensive
care: which is better?.
Curr Opin Nephrol Hypertens.
1999;
8
537-541
Reference Ris Wihthout Link
- 2
Allgren R L, Marbury C, Rahman S N. et al .
Anaritide in acute tubular necrosis.
N
Engl J Med.
1997;
336
828-834
Reference Ris Wihthout Link
- 3
Barrett B J, Carlisle E J.
Metaanalysis
of the relative nephrotoxicity of high and low-osmolality iodinated
contrast media.
Radiology.
1993;
188
171-178
Reference Ris Wihthout Link
- 4
Berns A S.
Nephrotoxicity
of contrast media.
Kidney Int.
1989;
36
730-740
Reference Ris Wihthout Link
- 5
Burke T J, Arnold P E, Gordon J A, Bulger R E, Dobyan D C, Schrier R W.
Protective
effect of intrarenal calcium membrane blockers before or after renal
ischemia.
J Clin Invest.
1984;
74
1830-1841
Reference Ris Wihthout Link
- 6
Chertow G M, Lazarus J M, Paganini E P, Allgren R L, Lafayette R A, Sayegh M H. The Auricullin
Anaritide Acute Renal Failure Study Group .
Predictors
of mortality and the provision of dialysis in patients with acute
tubular necrosis.
J Am Soc Nephrol.
1998;
9
692-698
Reference Ris Wihthout Link
- 7
Erley C M, Duda S H, Rehfuss D. et al .
Prevention of radiocontrast-media induced
nephropathy in patients with pre-existing renal insufficiency by
hydration in combination with the adenosine antagonist theophylline.
Nephrol
Dial Transplant.
1999;
14
1146-1149
Reference Ris Wihthout Link
- 8
Franklin S C, Moulton M, Sicard G A, Hammermann M R, Miller S B.
Insulin-like
growth factor I preserves renal function postoperatively.
Am
J Physiol.
1997;
272
F257-259
Reference Ris Wihthout Link
- 9
Hatala R, Dinh T, Cook D J.
Once-daily
aminoglycoside dosing in immunocompetent adults: A meta-analysis.
Ann
Intern med.
1996;
124
717-725
Reference Ris Wihthout Link
- 10
Hirschberg R, Kopple J, Lipsett P. et al .
Multicenter clinical trial of recombinant
human insulin-like growth factor I in patients with acute renal
failure.
Kidney Int.
1999;
55
2423-2432
Reference Ris Wihthout Link
- 11
Ichai C, Passeron C, Carles M, Bouregba M, Grimaud D.
Prolonged low-dose
dopamine infusion induces a transient improvement in renal function
in hemodynamically stable, critically ill patients: a single-blind,
prospective, controlled study.
Crit Care Med.
2000;
28
1329-1335
Reference Ris Wihthout Link
- 12
Jörres A, Gahl G M, Dobis C. et al .
Haemodialysis-membrane biocompatibility
and mortality of patients wih dialysis-dependent acute renal failure:
a prospective randomised multicentre trial.
Lancet.
1999;
354
1337-1341
Reference Ris Wihthout Link
- 13
Kellum J A.
Use
of diuretics in the acute care setting.
Kidney Int.
1998;
53
S67-S70
(Suppl 66))
Reference Ris Wihthout Link
- 14
Lassnigg A, Donner E, Grubhofer G, Presterl E, Druml W, Hiesmayr M.
Lack of renoprotective
effects of dopamine and furosemide during cardiac surgery.
J
Am Soc Nephrol.
2000;
11
97-104
Reference Ris Wihthout Link
- 15
Lehnert T, Keller E, Gondolf K, Schäffner T, Pavenstädt H, Schollmeyer P.
Effect of haemodialysis
after contrast medium administration in patients with renal insufficiency.
Nephrol
Dial Transplant.
1998;
13
358-362
Reference Ris Wihthout Link
- 16
Levy E M, Viscoli C M, Horwitz R I.
The
effect of acute renal failure on mortality: A cohort analysis.
JAMA.
1996;
275
1489-1494
Reference Ris Wihthout Link
- 17
Lewis J, Salem M M, Chertow G M, Weisberg L S, Mc Grew
F, Marbury T C, Allgren R L. Anaritide acute renal failure study group .
Atrial natriuretic
factor in oliguric acute renal failure.
Am J Kidney Dis.
2000;
36
767-774
Reference Ris Wihthout Link
- 18
Marik P E, Iglesias J. NORASEPT II Study Investigators .
Low-dose
dopamine does not prevent acute renal failure in patients with septic shock
and oliguria.
Am J Med.
1999;
107
387-390
Reference Ris Wihthout Link
- 19
Neumayer H H, Junge W, Kufner A, Wenning A.
Prevention
of radiocontrast-media induced nephrotoxicity by the calcium channel blocker
nitrendipine: A prospective randomized clinical trial.
Nephrol
Dial Transplant.
1989;
4
1030-1036
Reference Ris Wihthout Link
- 20
Noiri E, Peresleni T, Miller F, Goligorsky M S.
In vivo
targeting of inducible NO synthase with oligodeoxynucleotides protects
rat kidney against ischemia.
J Clin Invest.
1996;
97
2377-2383
Reference Ris Wihthout Link
- 21
Nolan C R, Anderson R J.
Hospital
aquired acute renal failure.
J Am Soc Nephrol.
1998;
9
710-718
Reference Ris Wihthout Link
- 22
Rabb H, O¿Meara Y, Maderna P, Coleman P, Brady H R.
Leucocytes, cell
adhesion molecules and ischemic acute renal failure.
Kidney Int.
1997;
51
1463-1468
Reference Ris Wihthout Link
- 23
Rahman S N, Kim G E, Mathew A S. et al .
Effects of atrial natriuretic peptide in
clinical acute renal failure.
Kidney Int.
1994;
45
1731-1738
Reference Ris Wihthout Link
- 24
Rodicio J L, Ruilope L M.
Assessing
renal effects and renal protection.
J Hypertens Suppl.
1995;
13
S19-S25
Reference Ris Wihthout Link
- 25
Ronco C, Bellomo R, Homl P. et al .
Effects of different doses in continous
veno-venous haemofilration on outcomes of acute renal failure: a
prospective randomised trial.
Lancet.
2000;
356
26-30
Reference Ris Wihthout Link
- 26
Rudnick M R, Berns J S, Cohen R M, Goldfarb S.
Contrast media-associated
nephrotoxicity.
Curr Opin Nephrol Hypertens.
1996;
5
127-123
Reference Ris Wihthout Link
- 27
Ruschitzka F, Shaw S, Gygi D, Noll G, Barton M, Lüscher T F.
Endothelial
dysfunction in acute renal failure: role of circulating and tissue
endothelin-1.
J Am Soc Nephrol.
1999;
10
953-962
Reference Ris Wihthout Link
- 28
Schiffl H, Lang S M, König A, Strasser T, Haider M C, Held E.
Biocompatible membranes
in acute renal failure: prospective case-controlled study.
Lancet.
1994;
344
570-572
Reference Ris Wihthout Link
- 29
Shilliday I R, Quinn K J, Allison M E.
Loop
diuretics in the management of acute renal failure: a prospective,
double-blind, placebo-contolled, randomized study.
Nephrol
Dial Transplant.
1997;
12
2592-2596
Reference Ris Wihthout Link
- 30
Singer I, Epstein M.
Potential of dopamine
A-1 agonists in the management of acute renal failure.
Am
J Kidney Dis.
1998;
31
743-755
Reference Ris Wihthout Link
- 31
Solomon R, Werner C, Mann D, D¿Elia J, Silva P.
Effects of saline, mannitol,
and furosemide on acute decreases in renal fuction induced by radiocontrast
agents.
N Engl J Med.
1994;
331
1416-1420
Reference Ris Wihthout Link
- 32
Tepel M, van der Giet M, Schwarzfeld C, Laufer U, Liermann D, Zidek W.
Prevention of radiographic-contrast-agent-induced
reductions in renal function by acetylcysteine.
N Engl
J Med.
2000;
343
180-184
Reference Ris Wihthout Link
- 33
Zager R A.
Rhabdomyolysis
and myohemoglobinuric acute renal failure.
Kidney Int.
1996;
45
314-326
Reference Ris Wihthout Link
1 Der Beitrag »Diagnostik des akuten Nierenversagens« ist im vorhergehenden Heft (Nr. 1/2) erschienen.
Korrespondenz
Dr. Stephan R. Lederer
Klinikum der Universität München, Medizinische
Klinik - Innenstadt
Ziemssenstraße 1
80336 München
Phone: 089/51602111
Fax: 089/51604924
Email: slederer@medinn.med.uni-muenchen.de