Microwave Enhanced Glaser Coupling Under Solvent Free Conditions
31 December 2001 (online)
A microwave enhanced, solvent free, Glaser coupling reaction has been developed. Self coupling of terminal alkynes on potassium fluoride-alumina in the presence of cupric chloride affords good yields of the corresponding diacetylenes.
Glaser coupling - microwave irradiation - terminal alkynes - potassium fluoride on alumina - cupric chloride