Enantioselective Aldol Reaction of Trimethoxysilyl Enol Ethers with Aldehydes Catalyzed by p-Tol-BINAP · AgF Complex
31 December 2001 (online)
New catalytic asymmetric Mukaiyama-type aldol reaction using trimethoxysilyl enol ethers was achieved using p-Tol-BINAP · AgF complex as a catalyst. High syn- and enantioselectivities were obtained both from the E- and Z-silyl enol ethers.
enantioselective aldol reaction - silyl enol ethers - aldehydes - BINAP · silver(I) complex - asymmetric catalysis