Synlett 2001; 2001(1): 0090-0092
DOI: 10.1055/s-2001-9714
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthetic Studies towards Mniopetals (III). Solid Phase Organic Synthesis of a Key Intermediate for Combinatorial Synthesis of Mniopetals, Kuehneromycins and Marasmanes

Ulrich Reiser* , Johann Jauch
  • *Institut für Organische Chemie und Biochemie, Technische Universität München, Lichtenbergstr. 4, 85747 Garching, Germany; Fax (0)89-289 13329; E-mail: Johann.Jauch§
Further Information

Publication History

Publication Date:
31 December 2001 (online)

The Solid Phase Organic Synthesis (SPOS) of an advanced building block for mniopetals, kuehneromycins, marasmanes and libraries thereof is presented. The synthesis is a sequence of a Michaelis-Arbuzov reaction, Horner-Wadsworth-Emmons reaction, hydroboration/oxidation, IBX oxidation, a new variant of the Baylis-Hillman reaction and a domino Dess-Martin oxidation/Intramolecular Diels-Alder reaction.