Synthetic Studies towards Mniopetals (II). A Short Synthesis of Mniopetal E
31 December 2001 (online)
A short total synthesis of Mniopetal E in thirteen steps is reported. Key steps are a new and highly diastereoselective lithium phenylselenide induced Baylis-Hillman reaction with Feringa's butenolide, an endo-selective intramolecular Diels-Alder reaction (IMDA) and a new variant of the Parikh-Doering oxidation.
Baylis-Hillman reactions - Diels-Alder reactions - furanones - natural products