Synlett 2001; 2001(1): 0132-0134
DOI: 10.1055/s-2001-9702
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Double Michael Reaction of N-Carboethoxy-2,3-dihydropyridin-4-one

Alessandra Giardini* , Giordano Lesma, Daniele Passarella, Maria Perez, Alessandra Silvani
  • *Dipartimento di Chimica Organica e Industriale - Università degli Studi di Milano, Centro CNR di Studio sulle Sostanze Organiche Naturali, Via Venezian 21, 20133 Milano, Italy; Fax 0039.02.2 36 76 06; E-mail: Passarel@icil64.cilea.it
Further Information

Publication History

Publication Date:
31 December 2001 (online)

Reaction of the enolate of N-ethoxycarbonyl-3,4-dihydropyridin-4-one with methyl acrylate provided N-ethoxycarbonyl-2-azabicyclo[2.2.2]-7-methoxycarbonyloctan-5-one by diastereoselective double Michael addition reaction.