Synlett 2001; 2001(1): 0126-0128
DOI: 10.1055/s-2001-9697
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Convenient Synthesis of a New Class of N2SO or N2S2 Tetradentate Ligands Suitable for Nuclear Medicine Applications

Loic Fourteau* , Eric Benoist, Michèle Dartiguenave
  • *Laboratoire de Chimie Inorganique, Université Paul Sabatier, Bat. IIR1, 118, route de Narbonne, 31062 Toulouse, France; Fax (33)-5-61-55-61-18; E-mail: benoist@ramses.ups-tlse.fr
Further Information

Publication History

Publication Date:
31 December 2001 (online)

In our search for a 99mTc labelled brain perfusion imaging agent, six new tetradentate acyclic ligands have been synthesised in good yield, through easy and fast syntheses. These compounds possess an aromatic ring bridging a nitrogen and an oxygen or a sulfur and contain two amides (1a, 1b) or an amine and an amide functionalities (2a-2d), which make them good candidates for radiopharmaceuticals.

    >