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Synlett 2001; 2001(1): 0135-0137
DOI: 10.1055/s-2001-9694
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A Preparative Route to Ethyl 3-(2-ethoxycarbonyl-1H-imidazol-4-yl) Propenoate and Propanoate

Marc Vuilhorgne* , Jean Bouquerel, Jean-Claude Hardy, Serge Mignani
  • *Aventis Pharma S.A., Centre de Recherche de Vitry-Alfortville, 13 quai Jules Guesde, B. P. 14, F-94403 Vitry-sur-Seine Cedex, France; Fax 33 1 55 71 80 14; E-mail: serge.mignani@aventis.com
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Publication History

Publication Date:
31 December 2001 (online)

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A facile route to ethyl 3-(2-ethoxycarbonyl-1H-imidazol-4-yl) propenoate and propanoate from commercially available 2,5-dihydro-2,5-dimethoxy furfurylamine is described.

ethyl 3-(2-ethoxycarbonyl-1H-imidazol-4-yl) propenoate - ethyl 3-(2-ethoxycarbonyl-1H-imidazol-4-yl) propanoate - 2,5-dihydro-2,5-dimethoxy furfurylamine - oxidation - hydrogenation

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