Diastereoselective Ce(III)-Catalyzed Pinacol Couplings of Aldehydes
31 December 2001 (online)
Aliphatic and aromatic aldehydes were converted into the corresponding pinacoles by using different cerium catalysts. Ce(OtBu)3 proved to be superior over other cerium(III) catalysts. Especially the highly diastereoselective pinacol coupling of sterically non demanding aldehydes such as hexanal is remarkable.
catalysis - cerium - diastereoselectivity - lanthanides - pinacol coupling