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Synlett 2001; 2001(11): 1793-1795
DOI: 10.1055/s-2001-18087
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A New Route to Butane-1,2-diacetals and the Development of Alternative Substitution Patterns to Facilitate Differential Protection of the Products

Steven V. Ley* , Patrick Michel
  • *Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK; Fax + 44(1223)33 64 42; E-mail: sv1000@cus.cam.ac.uk
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Publication History

Publication Date:
29 October 2001 (online)

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The utility of 2,3-dialkoxybutan-1,3-dienes as reagents for the protection of vicinal diols and α-hydroxy acids as their corresponding 1,2-diacetals is demonstrated together with their later deprotection under mild reaction conditions.

enol ether - 1,2-diol protection - α-hydroxy acid protection

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