InCl3-SiO2 Catalyzed Electrophilic Amination of Arenes: A Facile and Rapid Synthesis of Aryl Hydrazides
29 October 2001 (online)
Electron-rich arenes undergo electrophilic amination with diethyl azodicarboxylate on the surface of silica gel impregnated with indium trichloride in solvent-free conditions to afford para-substituted aryl hydrazides. Improved yields and enhanced rates are obtained by employing microwave irradiation.
InCl3-SiO2 - arenes - aryl hydrazides - microwaves