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Thorac Cardiovasc Surg 2001; 49(5): 259-267
DOI: 10.1055/s-2001-17795
Editorial
© Georg Thieme Verlag Stuttgart · New York

Does a Suitable Animal Model for Research on Partial Left Ventriculectomy Exist?

Animal Models for PLV[1] S. Christiansen1 , U. R. Jahn2 , J. Stypmann3 , K. Redmann4 , H. H. Scheld1 , D. Hammel1
  • 1Klinik und Poliklinik fur Thorax-, Herz- und Gefäßchirurgie
  • 2Klinik für Anästhesiologie und operative Intensivmedizin
  • 3Klinik und Poliklinik für Kardiologie und Angiologie
  • 4Experimentelle Thorax-, Herz- und Gefäßchirurgie
    Westfälische Wilhelms-Universität, Münster, Germany
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Publication History

Publication Date:
15 October 2001 (online)

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Partial left ventriculectomy is a new surgical option quickly introduced into clinical use worldwide for treating end-stage heart failure in patients with dilated cardiomyopathy. Due to the overwhelming success of this new kind of surgical treatment for dilated cardiomyopathy, experimental research on the physiological and pathophysiological basis was initially not performed. Now, demands for an appropriate animal model have arisen more and more since the outcome of patients treated by partial left ventriculectomy has differed considerably. This review summarizes available experimental models for heart failure in large animals, and discusses their suitability for research on partial left ventriculectomy.

Key words:

Animal model - Partial left ventriculectomy

1 This work was supported by the Deutsche Stiftung für Herzforschung, Frankfurt, Germany

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1 This work was supported by the Deutsche Stiftung für Herzforschung, Frankfurt, Germany

Dr. med. Stefan Christiansen

Klinik und Poliklinik für Thorax-, Herz- und Gefäßchirurgie
Westfälische Wilhelms-Universität Münster
Universität Münster

Albert-Schweitzer-Straße 33

48149 Münster

Germany

Phone: (+49) (251) 834-74 01

Fax: (+49) (251) 834-83 16

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