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DOI: 10.1055/s-2000-9107
Aktuelles zur Therapie der Karotisstenose
Publikationsverlauf
Publikationsdatum:
31. Dezember 2000 (online)

Nachdem im Jahr 1998 in zwei Artikeln zur Karotisstenose in der »Deutschen Medizinischen Wochenschrift« der damalige Standpunkt der Diagnostik und Therapie aufgezeigt wurde [25] [26], erscheint es nach der Veröffentlichung wichtiger neuerer Ergebnisse an der Zeit, eine aktuelle Ergänzung zu liefern. Der wesentliche Erkenntnisgewinn stammt aus den Auswertungen der beiden großen Studien zur Operation symptomatischer Karotisstenosen (KST) (NASCET-Studie: North American S ymptomatic Carotid E ndarterectomy Trial [1] , ECST-Studie: European C arotid Surgery Trial [2]), sowie aus den neueren Publikationen zur stentgestützten Dilatation als alternativem Behandlungsverfahren. Aufgrund der positiven Studienergebnisse hat die Zahl der Karotisoperationen deutlich zugenommen. Gleichzeitig sind die Komplikationsraten in vielen Zentren den in den großen Multizenterstudien erreichten Zahlen nähergekommen [12] [13] . Die Situation der operativen Versorgung der Karotisstenosen ist damit derzeit günstiger als noch vor Jahren.
Literatur
- 1
North American
Symptomatic Carotid Endarterectomy Trial Collaborators .
Beneficial
effect of carotid endarterectomy in symptomatic patients with high-grade
carotid stenosis.
N Engl J Med.
1991;
325
445-453
Reference Ris Wihthout Link
- 2
European Carotid Surgery Trialists
Collaborative Group .
MRC European Carotid Surgery Trial:
interim results for symptomatic patients with severe (70 - 99 %)
or with mild (0 - 29 %)
carotid stenosis.
Lancet.
1991;
337
1235-1243
Reference Ris Wihthout Link
- 3
European Carotid Surgery Trialists
Collaborative Group .
Randomised trial of endarterectomy
for recently symptomatic carotid stenosis: final results of the
MRC European Carotid Surgery Trial (ECST).
Lancet.
1998;
351
1379-1387
Reference Ris Wihthout Link
- 4
The SYMPHONY Investigators .
Comparison
of sibrafiban with aspirin for prevention of cardiovascular events
after acute coronary syndromes: a randomised trial.. Sibrafiban
versus Aspirin to Yield Maximum Protection from Ischemic Heart Events
Post-acute Coronary Syndromes.
Lancet.
2000;
355
337-345
Reference Ris Wihthout Link
- 5
Al Mubarak N, Roubin G S, Gomez C R. et al .
Carotid artery stenting in patients with
high neurologic risks.
Am J Cardiol.
1999;
83
1411-1419
Reference Ris Wihthout Link
- 6
Al Mubarak N, Roubin G S, Liu M W. et al .
Early results of percutaneous intervention
for severe coexisting carotid and coronary artery disease.
Am
J Cardiol.
1999;
84
600-602
Reference Ris Wihthout Link
- 7
Allenberg J, Brandt T, Thron A.
Perkutane
transluminale Angioplastie (PTA) und Stenting bei Stenosen der A.
carotis interna.
Nervenarzt.
1999;
70
314
Reference Ris Wihthout Link
- 8
Barnett H J, Taylor D W, Eliasziw M. et al .
Benefit of carotid endarterectomy in patients
with symptomatic moderate or severe stenosis. North American Symptomatic
Carotid Endarterectomy Trial Collaborators.
N Engl J Med.
1998;
339
1415-1425
Reference Ris Wihthout Link
- 9
Benavente O, Moher D, Pham B.
Carotid
endarterectomy for asymptomatic carotid stenosis: A meta- analysis.
BMJ.
1998;
317
1477-1480
Reference Ris Wihthout Link
- 10
Bennett C L, Weinberg P D, Rozenberg-Ben-Dror K, Yarnold P R, Kwaan H C, Green D.
Thrombotic thrombocytopenic
purpura associated with ticlopidine. A review of 60 cases.
Ann
Intern Med.
1998;
128
541-544
Reference Ris Wihthout Link
- 11
Bergeron P, Becquemin J P, Jausseran J M. et al .
Percutaneous stenting of the internal carotid
artery: The European CAST I Study. Carotid Artery Stent Trial.
J
Endovasc Surg.
1999;
6
155-159
Reference Ris Wihthout Link
- 12
Biller J, Feinberg W M, Castaldo J E. et al .
Guidelines for carotid endarterectomy:
a statement for healthcare professionals from a Special Writing
Group of the Stroke Council, American Heart Association.
Circulation.
1998;
97
501-509
Reference Ris Wihthout Link
- 13
Brittenden J, Murie J A, Jenkins A M, Ruckley C V, Bradbury A W.
Carotid
endarterectomy before and after publication of randomized controlled
trials.
Br J Surg.
1999;
86
206-210
Reference Ris Wihthout Link
- 14
Cao P, Giordano G, De Rango P. et al .
Eversion
versus conventional carotid endarterectomy: Late results of a prospective
multicenter randomized trial.
J Vasc Surg.
2000;
31
19-30
Reference Ris Wihthout Link
- 15
Carlsson J, Miketic S, Batge R, Riedel P, Rahlf G, Tebbe U.
Ticlopidine-associated
thrombotic thrombocytopenic purpura (Morbus Moschcowitz).
Med
Klin.
2000;
95
44-48
Reference Ris Wihthout Link
- 16
Castaldo J E.
Is
carotid endarterectomy appropriate for asymptomatic stenosis? Yes.
Arch
Neurol.
1999;
56
877-879
Reference Ris Wihthout Link
- 17 Chambers B R, You R X, Donnan G A. Carotid
endarterectomy for asymptomatic carotid stenosis. Cochrane
Database Syst Rev CD001923 2000
Reference Ris Wihthout Link
- 18
Chaturvedi S.
Is
carotid endarterectomy appropriate for asymptomatic stenosis? No.
Arch
Neurol.
1999;
56
879-881
Reference Ris Wihthout Link
- 19
Eckstein H H, Schumacher H, Klemm K. et al .
Emergency carotid endarterectomy.
Cerebrovasc
Dis.
1999;
9
270-281
Reference Ris Wihthout Link
- 20
Ferguson G G, Eliasziw M, Barr H W. et al .
The North American Symptomatic Carotid
Endarterectomy Trial: Surgical results in 1415 patients.
Stroke.
1999;
30
1751-1758
Reference Ris Wihthout Link
- 21
Giordano J M.
The
timing of carotid endarterectomy after acute stroke.
Semin
Vasc Surg.
1998;
11
19-23
Reference Ris Wihthout Link
- 22
Gorelick P B.
Carotid
endarterectomy: Where do we draw the line?.
Stroke.
1999;
30
1745-1750
Reference Ris Wihthout Link
- 23
Gorelick P B, Sacco R L, Smith D B. et al .
Prevention of a first stroke: A review
of guidelines and a multidisciplinary consensus statement from the
National Stroke Association.
JAMA.
1999;
281
1112-1120
Reference Ris Wihthout Link
- 24
Gross C M, Kramer J, Uhlich F. et al .
Treatment of carotid artery stenosis by
elective stent placement instead of carotid endarterectomy in patients
with severe coronary artery disease.
Thromb Haemost.
1999;
82
(Suppl 1)
176-180
Reference Ris Wihthout Link
- 25
Hamann G F.
Diagnostik
der extrakraniellen Karotisstenose.
Dtsch Med Wochenschr.
1998;
123
1075-1080
Reference Ris Wihthout Link
- 26
Hamann G F.
Therapie
der extrakraniellen Karotisstenose.
Dtsch Med Wochenschr.
1998;
123
1109-1115
Reference Ris Wihthout Link
- 27
Hankey G J.
Stroke:
How large a public health problem, and how can the neurologist help?.
Arch
Neurol.
1999;
56
748-754
Reference Ris Wihthout Link
- 28
Hobson R W, Brott T, Ferguson R. et al .
CREST: Carotid revascularization endarterectomy
versus stent trial.
Cardiovasc Surg.
1997;
5
457-458
Reference Ris Wihthout Link
- 29
Hoffmann M, Robbs J.
Carotid endarterectomy
after recent cerebral infarction.
Eur J Vasc Endovasc
Surg.
1999;
18
6-10
Reference Ris Wihthout Link
- 30
Inzitari D, Eliasziw M, Gates P. et al .
The causes and risk of stroke in patients
with asymptomatic internal-carotid-artery stenosis.
N Engl
J Med.
2000;
342
1693-1700
Reference Ris Wihthout Link
- 31
Kahn M B, Patterson H K, Seltzer J. et al .
Early carotid endarterectomy in selected
stroke patients.
Ann Vasc Surg.
1999;
13
463-467
Reference Ris Wihthout Link
- 32
Kappelle L J, Eliasziw M, Fox A J, Sharpe B L, Barnett H J.
Importance of
intracranial atherosclerotic disease in patients with symptomatic
stenosis of the internal carotid artery. The North American Symptomatic
Carotid Endarterectomy Trail.
Stroke.
1999;
30
282-286
Reference Ris Wihthout Link
- 33
Kistler J P, Furie K L.
Carotid endarterectomy
revisited.
N Engl J Med.
2000;
342
1743-1745
Reference Ris Wihthout Link
- 34
Lanzino G, Mericle R A, Lopes D K, Wakhloo A K, Guterman L R, Hopkins L N.
Percutaneous
transluminal angioplasty and stent placement for recurrent carotid
artery stenosis.
J Neurosurg.
1999;
90
688-694
Reference Ris Wihthout Link
- 35
Leisch F, Kerschner K, Hofman R, Bibl D, Engleder C, Bergmann H.
Carotid stenting: acute
results and complications.
Z Kardiol.
1999;
88
661-668
Reference Ris Wihthout Link
- 36
Liu A Y, Paulsen R D, Marcellus M L, Steinberg G K, Marks M P.
Long-term
outcomes after carotid stent placement treatment of carotid artery
dissection.
Neurosurgery.
1999;
45
1368-1373
Reference Ris Wihthout Link
- 37
Mathias K, Jäger H, Sahl H, Hennings S, Gißler H -M.
Die
endoluminale Therapie der Kaotisstenose.
Dt Ärztebl.
1999;
96
A-2502-A-2508
Reference Ris Wihthout Link
- 38
Ohki T, Roubin G S, Veith F J, Iyer S S, Brady E.
Efficacy of a filter device
in the prevention of embolic events during carotid angioplasty and
stenting: An ex vivo analysis.
J Vasc Surg.
1999;
30
1034-1044
Reference Ris Wihthout Link
- 39
Paciaroni M, Eliasziw M, Kappelle L J, Finan J W, Ferguson G G, Barnett H J.
Medical complications
associated with carotid endarterectomy. North American Symptomatic
Carotid Endarterectomy Trial (NASCET).
Stroke.
1999;
30
1759-1763
Reference Ris Wihthout Link
- 40
Papavasiliou A K, Magnadottir H B, Gonda T, Franz D, Harbaugh R E.
Clinical
outcomes after carotid endarterectomy: comparison of the use of
regional and general anesthetics.
J Neurosurg.
2000;
92
291-296
Reference Ris Wihthout Link
- 41
Patel S T, Haser P B, Korn P, Bush H L Jr, Deitch J S, Kent K C.
Is carotid endarterectomy
cost-effective in symptomatic patients with moderate (50 % to
69 %) stenosis?.
J Vasc Surg.
1999;
30
1024-1033
Reference Ris Wihthout Link
- 42
Qureshi A I, Luft A R, Janardhan V. et al .
Identification of patients at risk for
periprocedural neurological deficits associated with carotid angioplasty
and stenting.
Stroke.
2000;
31
376-382
Reference Ris Wihthout Link
- 43
Ricco J B, Illuminati G, Bouin-Pineau M H. et al .
Early carotid endarterectomy after a nondisabling
stroke: a prospective study.
Ann Vasc Surg.
2000;
14
89-94
Reference Ris Wihthout Link
- 44
Rothwell P M.
Carotid
endarterectomy for recently symptomatic carotid stenosis: consistent
results from two large randomized controlled trials.
Eur
Heart J.
1999;
20
1055-1057
Reference Ris Wihthout Link
- 45
Rothwell P M, Warlow C P. European Carotid
Surgery Trialists Collaborative Group .
Interpretation
of operative risks of individual surgeons.
Lancet.
1999;
353
1325
Reference Ris Wihthout Link
- 46
Rothwell P M, Warlow C P. European Carotid
Surgery Trialists Collaborative Group .
Prediction of
benefit from carotid endarterectomy in individual patients: A risk-modelling
study.
Lancet.
1999;
353
2105-2110
Reference Ris Wihthout Link
- 47
Roubin G S.
The
status of carotid stenting.
Am J Neuroradiol.
1999;
20
1378-1381
Reference Ris Wihthout Link
- 48
Schneider C, Johansen K, Konigstein R, Metzner C, Oettinger W.
Emergency
carotid thromboendarterectomy: Safe and effective.
World
J Surg.
1999;
23
1163-1167
Reference Ris Wihthout Link
- 49
Sievert H, Pfeil W, Bosenberg I, Spies H, Theis R, Beykirch K F.
Primäre
Stentversorgung der Arteria carotis interna.
Dtsch Med
Wochenschr.
1999;
124
1262-1266
Reference Ris Wihthout Link
- 50
Taylor D W, Barnett H J, Haynes R B. et al .
Low-dose and high-dose acetylsalicylic
acid for patients undergoing carotid endarterectomy: A randomised
controlled trial. ASA and Carotid Endarterectomy (ACE) Trial Collaborators.
Lancet.
1999;
353
2179-2184
Reference Ris Wihthout Link
- 51
Warlow C.
Carotid
endarterectomy for asymptomatic carotid stenosis. Better data, but
the case is still not convincing.
BMJ.
1998;
317
1468
Reference Ris Wihthout Link
- 52
Wholey M H, Wholey M, Bergeron P. et al .
Current global status of carotid artery
stent placement.
Cathet Cardiovasc Diagn.
1998;
44
1-6
Reference Ris Wihthout Link
Korrespondenz
Prof. Dr. Gerhard F. Hamann
Stroke-unit Neurologische Klinik Klinikum
Großhadern Ludwig-Maximillians-Universität
München
81366 München
Telefon: 089/7095-3670
Fax: 089/7095-3677
eMail: hamann@brain.nefo.med.uni-muenchen.de