Synthesis 2000; 2000(14): 2092-2098
DOI: 10.1055/s-2000-8732
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Synthesis of Enantioenriched Substituted Tetrahydrofurans and Tetrahydropyrans via Iron-Mediated Chirality Transfer and Ring Closure

Dieter Enders* , Duy Nguyen
  • *Institut für Organische Chemie, Rheinisch-Westfälische Technische Hochschule, Professor-Pirlet-Straße 1, D-52074 Aachen, Germany; Fax +49(241)8 88 81 27; E-mail: [email protected]
Further Information

Publication History

Publication Date:
31 December 2000 (online)

The synthesis of optically active, functionalized tetrahydrofurans and tetrahydropyrans via Fe(CO)4-mediated cycloetherification has been accomplished. The ring closure reaction proceeds with chirality transfer and under retention of the configuration at the allylic carbon center.