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A Practical and Highly Efficient Synthesis of α-(Trimethylsilyl)-difluoroacetates
31 December 2000 (online)
An efficient method for the gram scale preparation of α-(trimethylsilyl)difluoroacetates is described. The key step involves Mg(0)-promoted selective C-F bond cleavage of readily available trifluoroacetates.
magnesium - fluorine - silicon - esters - electron transfer