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A Highly Chemoselective Protection and Activation of Primary Amines in Polyamine
31 December 2000 (online)
Functionalization of polyamines containing both primary and secondary amine moieties could be achieved with the use of 2-nitrobenzenesulfonyl chloride. In the presence of a secondary amine, the primary amine groups are selectively transformed into the corresponding N-sulfonyl derivatives.
amines - protecting groups - sulfonamides - chemoselectivity