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Synlett 2000; 2000(3): 311-314
DOI: 10.1055/s-2000-6541
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First Efficient Regio- and Stereoselective Metal-Catalyzed Azidolysis of 2,3-Epoxycarboxylic Acids in Water

Francesco Fringuelli* , Ferdinando Pizzo, Luigi Vaccaro
  • *Università di Perugia, Dipartimento di Chimica, Via Elce di Sotto, 8-06123 Perugia, Italy; Fax +39-0 75-5 85 55 60; E-mail: pizzo@unipg.it
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Publication Date:
31 December 2000 (online)

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Azidolysis of 2,3-epoxycarboxylic acids occurs quantitatively and with complete regio- and stereoselectivity at C-3 in water as reaction medium in the presence of a catalytic amount of Cu(NO3)2.

azidolysis - catalysis - water - 2,3-epoxycarboxylic acids

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