Synthesis 2000; 2000(5): 655-660
DOI: 10.1055/s-2000-6385
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A Versatile Synthesis of Poly- and Diversely Substituted Isoindolin-1-ones

Christophe Hoarau* , Axel Couture, Eric Deniau, Pierre Grandclaudon
  • *Laboratoire de Chimie Organique Physique, ESA CNRS No 8009, Université des Sciences et Technologies de Lille, F-59655 Villeneuve d'Ascq Cédex, France; Fax + 33(0)3 20 33 63 09; E-mail: Axel.Couture@univ-lille1.fr
Further Information

Publication History

Publication Date:
31 December 2000 (online)

A variety of diversely substituted isoindolin-1-ones have been prepared by alkaline cleavage of the C-P pond in the corresponding phosphorylated lactams obtained by base-induced arynemediated cyclization of o-halogeno-N-(phosphinylmethyl)benzamide derivatives.