Synthesis 2000; 2000(6): 781-783
DOI: 10.1055/s-2000-6276
short paper
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Entrapment of Lipases in Hydrophobic Sol-Gel-Materials: Efficient Heterogeneous Biocatalysts in Aqueous Medium

Manfred T. Reetz* , Regina Wenkel, David Avnir
  • *Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, D-45470 Mülheim/Ruhr, Germany; Fax +49 (2 08) 3 06 29 85; E-mail:
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Publication History

Publication Date:
31 December 2000 (online)

The entrapment of certain lipases such as SP 525 (Candida antarctica B) or SP 523 (Humicola lanuginosa) in hydrophobic sol-gel materials derived from mixtures of RSi(OMe)3 (R = alkyl) and Si(OMe)4 or other alkyl-modified silane precursors results in heterogeneous biocatalysts which are remarkably active in the hydrolysis of esters in aqueous medium. Relative activities of 50-100% are typical.