Download PDF
Synlett 1999; 1999(10): 1563-1566
DOI: 10.1055/s-1999-2916
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Asymmetric Allylic Alkylation Using a Palladium Complex of Chiral 2-(Phosphinoaryl)pyridine Ligands

Katsuji Ito* , Risa Kashiwagi, Kazunori Iwasaki, Tsutomu Katsuki
  • *Department of Chemistry, Fukuoka University of Education, Akama, Munakata, Fukuoka 811-4192, Japan; Fax + 81-92-6 42-26 07
Further Information

Publication History

Publication Date:
31 December 1999 (online)

  PDF Download  Permissions and Reprints All articles of this category

A palladium complex of newly designed chiral 2-(phosphinoaryl)pyridine (4b) was found to be an effective catalyst for asymmetric allylic alkylation. High enantioselectivity was achieved in the reactions of both 1,3-diphenyl-2-propen-1-yl acetate (98% ee) and (2E)-1-methyl-2-butenyl phenyl carbonate (93% ee) with dimethyl malonate.

asymmetric allylic alkylations - asymmetric catalysis - palladium - chiral P,N-ligands

      >