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Synlett 1999; 1999(10): 1663-1666
DOI: 10.1055/s-1999-2908
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Raney Nickel: An Efficient Reagent to Achieve the Chemoselective Hydrogenation of α,β-Unsaturated Carbonyl Compounds

Alejandro F. Barrero* , E. J. Alvarez-Manzaneda, Rachid Chahboun, R. Meneses
  • *Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Granada, 18071 Granada (Spain); Fax + 34 58 24 33 18; E-mail: afbarre@goliat.ugr.es
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Publication Date:
31 December 1999 (online)

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Raney Nickel is an effective reagent to achieve the chemoselective reduction of conjugated olefins in α,β-unsaturated carbonyl compounds that also contain isolated double bonds. Its use is also compatible with a variety of other functional groups.

hydrogenation - 1,4-addition