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Synlett 1999; 1999(4): 498-500
DOI: 10.1055/s-1999-2642
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Lanthanide Triflates Catalyzed Reactions of Imines with Indole in Protic Media

Wenhua Xie* , Karen M. Bloomfield, Yafei Jin, Nicole Y. Dolney, Peng George Wang
  • *Department of Chemistry, Wayne State University, Detroit, MI 48202-3489, USA
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Publication Date:
31 December 1999 (online)

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Lanthanide triflates Ln(OTf)3 were found to catalyze the electrophilic substitution reactions of indole with a variety of imines in protic media, affording predominately secondary indolyl amines as well as bisindolyl methanes as by-products.

lanthanide triflate - catalysis - imine - indole - protic media

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