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Synlett 1999; 1999(2): 222-224
DOI: 10.1055/s-1999-2574
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Synthesis of Fused Heterocycles from β-Enaminonitrile and Carbonyl Compounds

Péter Nemes* , Barbara Balázs, Gábor Tóth, Pál Scheiber
  • *Department of Chemistry, University of Veterinary Science, H-1400 Budapest, P.O. Box 2, Hungary; Fax 3 61-3 42-65 18; E-mail: pnemes@ns.univet.hu
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Publication Date:
31 December 1999 (online)

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α,β-Unsaturated ketones and aldehydes react in alkaline solution with enamino nitrile 1 to afford a large variety of new N-heterocycles 3-9. Dehydration of the cyclisation products gave fused polycyclic 1,4-dihydropyridines.

β-enaminonitrile - enones - cyclisation - dehydration - benzoquinolizines

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