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Synlett 1998; 1998(4): 379-380
DOI: 10.1055/s-1998-37503
DOI: 10.1055/s-1998-37503
letter
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Synthesis of C-Substituted Cyclic Amines Using Azacycloalkyl Organozinc Reagents
Further Information
Publication History
Publication Date:
31 December 2000 (online)
Azetidine and piperidine derived organozinc species have been prepared from the corresponding azacycloalkyl iodides by direct Zn insertion. They have been shown to readily undergo Pd(0) mediated cross-coupling reactions and to transmetallate with CuCN.2LiCl.