Download PDF
Synlett 1998; 1998(10): 1123-1125
DOI: 10.1055/s-1998-1883
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A General Synthesis of 1-(Dialkylaminomethyl)indoles

Brian E. Love* , Binh T. Nguyen
  • *Department of Chemistry, East Carolina University, Greenville, NC 27858, USA; Fax (252)328-6210; E-mail: loveb@mail.ecu.edu
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

1-(N,N-Dialkylamino)methylindoles are prepared from the corresponding 1-(dialkylaminomethyl)benzotriazoles by treatment with indole and base. The aminoalkylation proceeds in high yield with good regioselectivity.

indole - benzotriazole - aminomethylation - protecting group - metallation directing group

      >