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Synlett 1998; 1998(9): 963-964
DOI: 10.1055/s-1998-1839
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N-Acyl `Quat' Pyrrolidinone Auxiliary as a Chiral Amide Equivalent via Direct Aminolysis

Stephen G. Davies* , Darren J. Dixon
  • *Dyson Perrins Laboratory, University of Oxford, South Parks Road, Oxford OX1 3QY, UK
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Publication Date:
31 December 2000 (online)

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A novel route into chiral amides is achieved through the efficient, non-racemising, cleavage of N-acyl side chains from a `Quat' pyrrolidinone chiral auxiliary using a range of N-nucleophiles.

aminolysis - `Quat' chiral auxiliary - amides

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