Synlett 1998; 1998(9): 998-1000
DOI: 10.1055/s-1998-1828
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Directed Palladium-Catalyzed Cascade Cyclization as an Approach to trans- and cis-Hexahydro-1H-benz[f]indenes

Isabelle Coudanne* , Geneviève Balme
  • *Laboratoire de chimie organique I, associé au CNRS, Université Claude Bernard, CPE, 43 Bd du 11 Novembre 1918, 69622 Villeurbanne, France; Fax Int.; E-mail:
Further Information

Publication History

Publication Date:
31 December 2000 (online)

The hydrogenation of the acetylenic substrate 6 followed by a palladium-catalyzed cascade bis-cyclization process led to a trans-hexahydro-1H-benz[f]indene. By changing the order of the two preceding steps, only the cis-hexahydro-1H-benz[f]indene structure was obtained.