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Synlett 1998; 1998(7): 761
DOI: 10.1055/s-1998-1774
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Solid Phase Synthesis of Hydroxamic Acids

Sharon M. Dankwardt*
  • *Roche Bioscience, Inflammatory Disease Unit, Parallel Synthesis Group, 3401 Hillview Ave, Palo Alto, California 94304
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Publikationsdatum:
31. Dezember 2000 (online)

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The solid phase synthesis of hydroxamic acids is presented. Carboxylic acid ester linked, polymer-supported CBZ-protected amino acids were displaced from the resin with aqueous hydroxylamine to provide the corresponding hydroxamic acids.

polymer-supported - solid-phase - hydroxamic acid - ArgoGel