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Synlett 1998; 1998(6): 609-610
DOI: 10.1055/s-1998-1748
DOI: 10.1055/s-1998-1748
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© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved.
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data processing and storage.Incorporation of α-Substituted Serine Analog into Peptide via a Novel O,N-Migration
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Publication History
Publication Date:
31 December 2000 (online)
Peptides incorporating β-hydroxy-α,α-disubstituted-α-amino acids, (S)-α-methylserine ((S)-α-MeSer), (1R,2S)-1-amino-2-hydroxy-cyclohexanecarboxylic acid ((1R,2S)-Ahh), or (R)-α-benzyl-serine ((R)-α-BnSer), were efficiently synthesized using a novel O,N-migration.
O,N-migration - acyl migration - α-substituted serine - peptide synthesis