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Synlett 1998; 1998(5): 507-509
DOI: 10.1055/s-1998-1694
DOI: 10.1055/s-1998-1694
letter
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A Formal Synthesis of (-)-α-Kainic Acid
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Publikationsverlauf
Publikationsdatum:
31. Dezember 2000 (online)
The formal synthesis of (-)-α-kainic acid was achieved from L-pyroglutamic acid. The C-4 substituent of the pyrrolidine ring was introduced by using a ketyl radical cyclization on an enecarbamate.
(-)-α-kainic acid - radical - cyclization - synthesis - L-pyroglutamic acid