Synlett 1998; 1998(3): 316-318
DOI: 10.1055/s-1998-1631
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of Calystegine B2 Analogs by Tandem Tautomerization-Intramolecular Glycosylation of Thioureidosugars

J. M. García Fernández* , C. Ortiz Mellet, J. M. Benito, J. Fuentes
  • *Instituto de Investigaciones Químicas, CSIC, Américo Vespucio s/n, Isla de la Cartuja, E-41092 Sevilla, Spain; Fax 34 5 446 05 65; E-mail: jogarcia@cica.es
Further Information

Publication History

Publication Date:
31 December 2000 (online)

Ring-modified analogs of calystegine B2, a powerful glycosidase inhibitor of the polyhydroxy-nor-tropane series, have been prepared in one-pot reaction from thiourea-carbohydrate precursors via a tandem tautomerization-intramolecular glycosylation process.

    >