Subscribe to RSS
A Useful Oxidation Procedure for the Preparation of 3-Alkanoyltetronic Acids
31 December 2000 (online)
An easy and convenient synthesis of 3-alkanoyl-5-hydroxymethyltetronic acids, the salts of which have inhibitory activity against HIV-1 protease, is described and a new direct route to 1,3-dicarbonylester from cyclic β-ketoester is developed.
tetronic acid - selenide - oxidation - acylation - HIV-1 protease