Synlett 1997; 1997(4): 390-392
DOI: 10.1055/s-1997-798
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Stereocontrolled Mukaiyama-type Aldol Reaction of Siloxypyrroles Derived from (S)-Glutamic Acid

Hidemitsu Uno, Jack E. Baldwin* , Ian Churcher, Andrew T. Russell
  • *The Dyson Perrins Laboratory and The Oxford Centre for Molecular Sciences, South Parks Road, Oxford OX1 3QY, UK, Fax +44 1865 275674
Further Information

Publication History

Publication Date:
31 December 2000 (online)

The stereochemistry of the Lewis acid catalysed Mukaiyama-type aldol reaction of 5-tert-butyldimethylsiloxy-3-phenyl-1H-pyrrolo[1,2-e]oxazoles with isobutyraldehyde was dependant on the nature of the Lewis acid, SnCl4 and BF3•OEt2 giving predominantly isomeric products.