Download PDF
Synlett 1997; 1997(7): 775-776
DOI: 10.1055/s-1997-5781
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of α,β-Unsaturated Selenoamides by the Condensation Reaction of Lithium Eneselenolate Generated from Selenoacetamide with Aldehydes

Toshiaki Murai* , Tatsuya Ezaka, Toshio Ichimiya, Shinzi Kato
  • *Department of Chemistry, Faculty of Engineering, Gifu University, Yanagido, Gifu 501-11, Japan, Fax 58 230 1893; e-mail toshi@apchem.gifu-u.ac.jp
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

The reaction of lithium eneselenolate generated from selenoacetamide and LDA with aldehydes gave α,β-unsaturated selenoamides in good to high yields. The successive addition of n-butyllithium and 3-bromo-1-propene to α,β-unsaturated selenoamide 3a gave selenoamide 7 with high selectivity.

selenoacetamide - α,β-unsaturated selenoamides - aldol type condensation

      >