Download PDF
Synthesis 1997; 1997(9): 1010-1012
DOI: 10.1055/s-1997-1314
short paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of the Bifunctional Chelating Agent 6-(4-Aminobenzyl)-1,4,8,11-tetra-azacyclotetradecan-N,N',N'',N'''-tetraacetic Acid (H2NBn-TETA)

P. Moreau*
  • *The Guelph-Waterloo Center for Graduate Work in Chemistry, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

An improved, five-step synthesis (7% overall yield) of 6-(4-aminobenzyl)-1,4,8,11-tetraazacyclotetradecane-N,N',N'',N'''-tetraacetic acid (H2NBn-TETA, 6), an azamacrocyclic ligand used as a radionuclide carrier in cancer chemotherapy, is reported and its complete characterization and purification is for the first time described.

azamacrocycles

      >