Download PDF
Synthesis 1997; 1997(8): 874-876
DOI: 10.1055/s-1997-1285
short paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of Alkynyl Ketones via Palladium- and Copper-Catalyzed Carbonylative Cross Coupling of Iodonium Salts with Alk-1-ynes

Suk-Ku Kang* , Kwon-Ho Lim, Pil-Su Ho, Won-Yeob Kim
  • *Department of Chemistry, Sung Kyun Kwan University, Natural Science Campus, Suwon 440-746, Korea, Fax +82(331)2907074; E-mail: skkdng@chem.skku.ac.kr
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

The palladium- and copper-catalyzed coupling of iodonium salts with alk-1-ynes in the presence of atmospheric pressure of carbon monoxide in DME/H2O (4:1) and Pd(OAc)2 (0.2 mol%) [or Pd(OAc)2 with CuI (10 mol%) and NaHCO3 (1.2 equiv)], or CuI (10 mol%) and NaHCO3 (2.2. equiv) at 30°C afforded α,β-acetylenic ketones.

palladium-catalyzed carbonylative cross coupling - iodonium salts - copper-catalyzed carbonylative coupling

      >