Download PDF
Synthesis 1997; 1997(8): 891-894
DOI: 10.1055/s-1997-1280
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Facile and Efficient Deoxygenation of Aromatic N-Oxides with Zinc and Aqueous Ammonium Chloride

Yutaka Aoyagi, Tomomitsu Abe, Akihiro Ohta*
  • *School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-03, Japan, Fax +81(426)763040
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

Several aromatic N-oxides such as pyrazine, arylpyridine and quinoline N-oxides have been deoxygenated to parent amines under mild and efficient conditions using zinc and aqueous ammonium chloride in tetrahydrofuran.

zinc - ammonium chloride - deoxygenation - aromatic N-oxide - pyrazine N-oxide

      >