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Synlett 1996; 1996(12): 1201-1202
DOI: 10.1055/s-1996-5712
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A New Synthesis of 3-Methylidenetetrahydrofurans

M. Gordaliza* , J. M. Miguel del Corral, M. A. Castro, M. A. Salinero, A. San Feliciano, J. M. Dorado, F. Valle
  • *Departamento de Química Orgánica, Facultad de Farmacia, Universidad de Salamanca, Avda. Campo Carro s/n. 37007 Salamanca, Spain, Fax 34 23 294515, E-mail mliza@gugu.usal.es
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Publication History

Publication Date:
31 December 2000 (online)

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2-Aryl(Heteroaryl)-3-methylidenetetrahydrofurans can be readily prepared by a one-pot reduction-etherification protocol using 2-aryl (heteroaryl)methylidenesuccinates which are accessed using the Stobbe reaction.

2-Aryl-3-Methylidenetetrahydrofurans - allylic nucleophilic substitution

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