Download PDF
Synlett 1996; 1996(10): 969-970
DOI: 10.1055/s-1996-5655
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of Tris-Bridged Cyclic Hexapeptide Containing Hydrophilic Amino Acid Residues as an Active Site of Lipase

Hiroshi Uchida, Kazuo Achiwa*
  • *School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Schizuoka 422, Japan
Further Information

Publication History

Publication Date:
31 December 2000 (online)

 PDF Download  Permissions and Reprints All articles of this category

Tris-bridged cyclic hexapeptide containing hydrophilic amino acid residues as an active site of lipase was synthesized from the piperazin-2-one derivatives which were obtained by treatment of the corresponding substituted dipeptides with p-toluenesulfonic acid or trifluoroacetic acid in toluene.

cyclic peptide - ethylene-bridge - piperazin-2-one - lipase