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Synlett 1995; 1995(12): 1277-1279
DOI: 10.1055/s-1995-5243
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The Synthesis and Some Ring-Opening Reactions of N,O-bis(Diphenylphosphinyl) HydroxymethylAziridine

Alex A. Cantrill, J. B. Sweeney*
  • *School of Chemistry, University of Bristol, Cantocks Close, Bristol BS8 1TS, U.K.
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Publication Date:
31 December 2000 (online)

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The synthesis of N,O-bis(diphenylphosphinyl) hydroxymethylaziridine (‘Di-Dpp’) (1) may be accomplished in ‘one-pot’ from 2-amino-1,3-dihydroxypropane. (1) Undergoes either single or double alkylation upon reaction with copper-modified Grignard reagents.

Aziridine - ring-opening - diphenylphosphinyl

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