Synlett 1995; 1995(10): 1029-1030
DOI: 10.1055/s-1995-5158
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Combination of the ADH with a Two-dimensional Synthesis

Martin E. Maier* , Sebastian Reuter
  • *Martin-Luther-Universität Halle-Wittenberg, Fachbereich Chemie, Institut für Organische Chemie, Weinbergweg 16, 06120 Halle (Saale), Germany
Further Information

Publication History

Publication Date:
31 December 2000 (online)

Asymmetric dihydroxylation of the symmetrical diester 1 provided after lactonization the C2-symmetric bis-lactone 3. The chiral information was then propagated by a double alkylation reaction. After conversion of the alkylated bis-lactone 4a to the diol 8, a cleavage reaction provided the chiral building block 9.