Download PDF
Synlett 1995; 1995(8): 853-854
DOI: 10.1055/s-1995-5093
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Tetrabutylammonium Dihydrogentrifluoride as a Powerful Catalyst in the Regioselective Opening of Epoxides with Activated Aromatic and Heteroaromatic Chlorides

D. Albanese, D. Landini, A. Maia, M. Penso*
  • *Centro CNR and Dipartimento di Chimica Organica e Industriale dell’Università, Via Golgi 19, I-20133 Milano, Italy, Fax +2 236 4369; research%iumchz@imiclvx.bitnet
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

Tetrabutylammonium dihydrogentrifluoride, Bu4N+H2F3-, was found to be a very efficient catalyst in the ring opening of epoxides by aromatic or heteroaromatic chlorides to prepare the corresponding 2-aryloxy- or 2-heteroaryloxy-1-chloroalkyl derivatives 8 in 62-87% yield, by operating at 90 °C without solvent.

Tetrabutylammonium Dihydrogentrifluoride - Epoxides - Ring Opening - Regioselective - Aromatic Chlorides

      >