Download PDF
Synlett 1995; 1995(8): 837-838
DOI: 10.1055/s-1995-5083
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Remarkable Kinetic Resolution of Chiral β-Keto Esters by Baker’s Yeast Reduction

Marcus Eh, Markus Kalesse*
  • *Institut für Organische Chemie, Universität Hannover, Schneiderberg 1b, D-30167 Hannover, Germany, Fax: +49-511 7624643, Email: Kalesse@mbox.oci.uni-hannover.de
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

The reduction of chiral β-keto esters with baker’s yeast is described. Reduction of 10 yields highly functionalized diol 11 with excellent stereoselectivity and generates a useful intermediate for natural product syntheses.

Baker’s yeast reduction - β-keto esters - kinetic resolution - 1,3-diols

      >