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Synlett 1995; 1995(4): 315-316
DOI: 10.1055/s-1995-4969
DOI: 10.1055/s-1995-4969
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A Simple and Practical Synthesis of 1-β-Methylcarbapenems Based on the Counterattack Strategy
Further Information
Publication History
Publication Date:
31 December 2000 (online)
A convenient synthesis of 1-β-methylcarbapenems from thioesters via chlorotrimethylsilane mediated Dieckmann-type cyclization followed by counterattack of thiolate anion is described.
1-β-methylcarbapenem - counterattack reagent - Dieckmann-type cyclization