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Synlett 1995; 1995(2): 159-160
DOI: 10.1055/s-1995-4903
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A SIMPLE METHOD FOR THE SELECTIVE MOM PROTECTION OF THIOLS

F. Dean Toste* , Ian W. J. Still1
  • *J. Tuzo Wilson Research Laboratories, Erindale College, University of Toronto in Mississauga, Mississauga, Ontario, Canada L5L 1C6
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Publication History

Publication Date:
31 December 2000 (online)

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Thiols are MOM-protected using bromochloromethane and methanol under phase-transfer catalysis with benzyltriethylammonium chloride. Under the same conditions alcohols and carboxylic acids are recovered unchanged.

thiols - protection - MOM - chemoselectivity - phase-transfer

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