Synlett 1995; 1995(2): 142-144
DOI: 10.1055/s-1995-4901
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

The Enantioselective Synthesis of Neopentylamine Derivatives

Neil Moss* , Jean Gauthier, Jean-Marie Ferland
  • *Bio-Méga/Boehringer Ingelheim Research Inc., 2100 Cunard, Laval, Quebec, Canada, H7S 2G5
Further Information

Publication History

Publication Date:
31 December 2000 (online)

Enantiomerically pure neopentylamine derivatives 1 can be readily prepared from ketones 2 by a four step sequence involving imine formation with R-α-methylbenzylamine followed by a highly diastereoselective reduction with NaBH4.

    >