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Synthesis 1995; 1995(3): 285-293
DOI: 10.1055/s-1995-3905
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General Synthesis of Retinoids and Arotinoids via Palladium-Catalyzed Cross-Coupling of Boronic Acids with Electrophiles

Alicia Torrado, Susana López, Rosana Alvarez, Angel R. de Lera*
  • *Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15706 Santiago de Compostela, Spain, Fax +34(81)595012; E-Mail golera@usc.es
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Publication Date:
31 December 2000 (online)

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A novel approach to the synthesis of retinoids and arotinoids (including heterocyclic analogs) is described which is based on the thallium-accelerated palladium-catalyzed cross-coupling of boronic acids with a variety of electrophiles (the Suzuki reaction).

retinoids - arotinoids - Suzuki coupling - boronic acids - electrophiles

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