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Synlett 1994; 1994(8): 665-666
DOI: 10.1055/s-1994-22968
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Palladium-mediated Homologation of Optically Active (E)-2-Chlorovinylcarbinols

Yoshiaki Sugihara* , Kunio Ogasawara
  • *Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-77, Japan
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Publication History

Publication Date:
18 September 2002 (online)

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General route to optically active (E)-allylic alcohols has been developed by a palladium-mediated replacement of the 2-chloro group on optically active (E)-2-chlorovinylcarbinols of which efficient preparation was established recently.

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