Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000083.xml
Synlett 1994; 1994(4): 245-246
DOI: 10.1055/s-1994-22812
DOI: 10.1055/s-1994-22812
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved.
This journal, including all individual contributions and illustrations published
therein, is legally protected by copyright for the duration of the copyright period.
Any use, exploitation or commercialization outside the narrow limits set by copyright
legislation, without the publisher's consent, is illegal and liable to criminal prosecution.
This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing
or duplication of any kind, translating, preparation of microfilms, and electronic
data processing and storage.New Synthesis of Phthalideisoquinoline Alkaloids via a Stereoselective Hydride Reduction of 1-(2′-Bromobenzoyl)-3,4-dihydroisoquinoline Methiodide, followed by Palladium-Catalyzed Carbonylation aided by Chlorotrimethylsilane
Further Information
Publication History
Publication Date:
22 March 2002 (online)
PDF Download(opens in new window) Permissions and Reprints(opens in new window) All articles of this category(opens in new window)

A new method for the synthesis of phthalideisoquinoline alkaloids by the stereoselective reduction of 1-(2′-bromobenzoyl)-3,4-dihydroisoquinoline methiodide (4a) with sodium borohydride or lithium aluminium hydride, followed by a palladium-catalyzed carbonylation of the resultant erythro or threo alcohol (6a, 7) in the presence of chlorotrimethylsilane, is reported.