Synlett 1994; 1994(3): 187-188
DOI: 10.1055/s-1994-22788
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An Alternative Route to Aryloxymethylphosphonates and Phosphinates via Fluoride Ion Displacement from Activated Aromatic Substrates

John Berge* , George N. Moore
  • *Department of Medicinal Chemistry, SmithKline Beecham, Yew Tree Bottom Road, Epsom, Surrey, KT18 5XQ, UK.
Further Information

Publication History

Publication Date:
22 March 2002 (online)

Dialkyl aryloxymethylphosphonates and phosphinates can be prepared in a single step by the reaction of activated fluorobenzenes with dialkyl hydroxymethylphosphonates or phosphinates.

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